There are multiple ways of tracking a single molecule/particle using light. At present, a few of these techniques require the tracked molecule to have a fluorescence mechanism, but this limits the set of particles that can be tracked as not all single molecules fluoresce. A technique not limited by this requirement is interferometric scattering, iSCAT. Depending only on the particle in question’s ability to scatter light, this technique broadens the set of particles that can be studied. This technique is not without its own limits. One of which is the immense problem that signal noise presents. Machine learning and other modeling processes will be used to develop a iSCAT set-up that can do single particle tracking in real time over three dimensions.
MSc in Astrophysics, 2024
North-West University
BSc (Hons) in Physics, 2022
North-West University
BSc in Physics, 2021
North-West University